Treatment Of Sunitinib-Induced Hypertension In Solid Tumors By Nitric Oxid Donors
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چکیده
منابع مشابه
Treatment of sunitinib-induced hypertension in solid tumor by nitric oxide donors☆
Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) are overexpressed in the majority of renal cell carcinomas. This characteristic has supported the rationale of targeting VEGF-driven tumour vascularization, especially in clear cell RCC. VEGF-inhibiting strategies include the use of tyrosine kinase inhibitors (sunitinib, axitinib, pazopanib, and sorafenib) and neutralizing antib...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2015
ISSN: 2213-2317
DOI: 10.1016/j.redox.2015.09.036